Cross-species transmission of the newly identified coronavirus 2019-nCoV.
Identifieur interne : 000443 ( new/Analysis ); précédent : 000442; suivant : 000444Cross-species transmission of the newly identified coronavirus 2019-nCoV.
Auteurs : Wei Ji [République populaire de Chine] ; Wei Wang [République populaire de Chine] ; Xiaofang Zhao [République populaire de Chine] ; Junjie Zai [République populaire de Chine] ; Xingguang Li [République populaire de Chine]Source :
- Journal of medical virology [ 1096-9071 ] ; 2020.
Descripteurs français
- KwdFr :
- Animaux, Bungarus (génétique), Bungarus (virologie), Chiroptera (génétique), Chiroptera (virologie), Flambées de maladies, Glycoprotéine de spicule des coronavirus (génétique), Génome viral, Humains, Infections à coronavirus (transmission), Infections à coronavirus (virologie), Infections à coronavirus (épidémiologie), Phylogénie, Pneumopathie virale (transmission), Pneumopathie virale (virologie), Pneumopathie virale (épidémiologie), Recombinaison homologue, Réservoirs d'agents pathogènes, Serpents (génétique), Serpents (virologie), Spécificité d'hôte, Zoonoses, Évolution moléculaire.
- MESH :
- génétique : Bungarus, Chiroptera, Glycoprotéine de spicule des coronavirus, Serpents.
- virologie : Bungarus, Chiroptera, Infections à coronavirus, Pneumopathie virale, Serpents.
- épidémiologie : Infections à coronavirus, Pneumopathie virale.
- Animaux, Flambées de maladies, Génome viral, Humains, Phylogénie, Recombinaison homologue, Réservoirs d'agents pathogènes, Spécificité d'hôte, Zoonoses, Évolution moléculaire.
English descriptors
- KwdEn :
- Animals, Betacoronavirus (classification), Betacoronavirus (genetics), Betacoronavirus (physiology), Bungarus (genetics), Bungarus (virology), Chiroptera (genetics), Chiroptera (virology), Codon Usage, Coronavirus Infections (epidemiology), Coronavirus Infections (transmission), Coronavirus Infections (virology), Disease Outbreaks, Disease Reservoirs, Evolution, Molecular, Genome, Viral, Homologous Recombination, Host Specificity, Humans, Naja naja (genetics), Naja naja (virology), Phylogeny, Pneumonia, Viral (epidemiology), Pneumonia, Viral (transmission), Pneumonia, Viral (virology), Snakes (genetics), Snakes (virology), Spike Glycoprotein, Coronavirus (genetics), Zoonoses.
- MESH :
- chemical , genetics : Spike Glycoprotein, Coronavirus.
- classification : Betacoronavirus.
- epidemiology : Coronavirus Infections, Pneumonia, Viral.
- genetics : Betacoronavirus, Bungarus, Chiroptera, Naja naja, Snakes.
- physiology : Betacoronavirus.
- transmission : Coronavirus Infections, Pneumonia, Viral.
- virology : Bungarus, Chiroptera, Coronavirus Infections, Naja naja, Pneumonia, Viral, Snakes.
- Animals, Codon Usage, Disease Outbreaks, Disease Reservoirs, Evolution, Molecular, Genome, Viral, Homologous Recombination, Host Specificity, Humans, Phylogeny, Zoonoses.
Abstract
The current outbreak of viral pneumonia in the city of Wuhan, China, was caused by a novel coronavirus designated 2019-nCoV by the World Health Organization, as determined by sequencing the viral RNA genome. Many initial patients were exposed to wildlife animals at the Huanan seafood wholesale market, where poultry, snake, bats, and other farm animals were also sold. To investigate possible virus reservoir, we have carried out comprehensive sequence analysis and comparison in conjunction with relative synonymous codon usage (RSCU) bias among different animal species based on the 2019-nCoV sequence. Results obtained from our analyses suggest that the 2019-nCoV may appear to be a recombinant virus between the bat coronavirus and an origin-unknown coronavirus. The recombination may occurred within the viral spike glycoprotein, which recognizes a cell surface receptor. Additionally, our findings suggest that 2019-nCoV has most similar genetic information with bat coronovirus and most similar codon usage bias with snake. Taken together, our results suggest that homologous recombination may occur and contribute to the 2019-nCoV cross-species transmission.
DOI: 10.1002/jmv.25682
PubMed: 31967321
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 000C44
- to stream PubMed, to step Curation: 000C44
- to stream PubMed, to step Checkpoint: 000795
- to stream Ncbi, to step Merge: 000912
- to stream Ncbi, to step Curation: 000912
- to stream Ncbi, to step Checkpoint: 000912
- to stream Main, to step Merge: 000857
- to stream Main, to step Curation: 000855
- to stream Main, to step Exploration: 000855
- to stream new, to step Extraction: 000443
Links to Exploration step
pubmed:31967321Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Cross-species transmission of the newly identified coronavirus 2019-nCoV.</title><author><name sortKey="Ji, Wei" sort="Ji, Wei" uniqKey="Ji W" first="Wei" last="Ji">Wei Ji</name><affiliation wicri:level="3"><nlm:affiliation>Department of Microbiology, Peking University Health Science Center School of Basic Medical Sciences, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Microbiology, Peking University Health Science Center School of Basic Medical Sciences, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Wang, Wei" sort="Wang, Wei" uniqKey="Wang W" first="Wei" last="Wang">Wei Wang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Spleen and Stomach Diseases, The First affiliated Hospital of Guangxi University of Chinese Medicine, Nanning, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Spleen and Stomach Diseases, The First affiliated Hospital of Guangxi University of Chinese Medicine, Nanning</wicri:regionArea><wicri:noRegion>Nanning</wicri:noRegion></affiliation></author><author><name sortKey="Zhao, Xiaofang" sort="Zhao, Xiaofang" uniqKey="Zhao X" first="Xiaofang" last="Zhao">Xiaofang Zhao</name><affiliation wicri:level="1"><nlm:affiliation>Department of Science and Technology, Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine, Nanning, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Science and Technology, Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine, Nanning</wicri:regionArea><wicri:noRegion>Nanning</wicri:noRegion></affiliation></author><author><name sortKey="Zai, Junjie" sort="Zai, Junjie" uniqKey="Zai J" first="Junjie" last="Zai">Junjie Zai</name><affiliation wicri:level="1"><nlm:affiliation>Immunology Innovation Team, School of Medicine, Ningbo University, Ningbo, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Immunology Innovation Team, School of Medicine, Ningbo University, Ningbo</wicri:regionArea><wicri:noRegion>Ningbo</wicri:noRegion></affiliation></author><author><name sortKey="Li, Xingguang" sort="Li, Xingguang" uniqKey="Li X" first="Xingguang" last="Li">Xingguang Li</name><affiliation wicri:level="3"><nlm:affiliation>Hubei Engineering Research Center of Viral Vector, Wuhan University of Bioengineering, Wuhan, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Hubei Engineering Research Center of Viral Vector, Wuhan University of Bioengineering, Wuhan</wicri:regionArea><placeName><settlement type="city">Wuhan</settlement><region type="région">Hubei</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:31967321</idno><idno type="pmid">31967321</idno><idno type="doi">10.1002/jmv.25682</idno><idno type="wicri:Area/PubMed/Corpus">000C44</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000C44</idno><idno type="wicri:Area/PubMed/Curation">000C44</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000C44</idno><idno type="wicri:Area/PubMed/Checkpoint">000795</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000795</idno><idno type="wicri:Area/Ncbi/Merge">000912</idno><idno type="wicri:Area/Ncbi/Curation">000912</idno><idno type="wicri:Area/Ncbi/Checkpoint">000912</idno><idno type="wicri:Area/Main/Merge">000857</idno><idno type="wicri:Area/Main/Curation">000855</idno><idno type="wicri:Area/Main/Exploration">000855</idno><idno type="wicri:Area/new/Extraction">000443</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Cross-species transmission of the newly identified coronavirus 2019-nCoV.</title><author><name sortKey="Ji, Wei" sort="Ji, Wei" uniqKey="Ji W" first="Wei" last="Ji">Wei Ji</name><affiliation wicri:level="3"><nlm:affiliation>Department of Microbiology, Peking University Health Science Center School of Basic Medical Sciences, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Microbiology, Peking University Health Science Center School of Basic Medical Sciences, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Wang, Wei" sort="Wang, Wei" uniqKey="Wang W" first="Wei" last="Wang">Wei Wang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Spleen and Stomach Diseases, The First affiliated Hospital of Guangxi University of Chinese Medicine, Nanning, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Spleen and Stomach Diseases, The First affiliated Hospital of Guangxi University of Chinese Medicine, Nanning</wicri:regionArea><wicri:noRegion>Nanning</wicri:noRegion></affiliation></author><author><name sortKey="Zhao, Xiaofang" sort="Zhao, Xiaofang" uniqKey="Zhao X" first="Xiaofang" last="Zhao">Xiaofang Zhao</name><affiliation wicri:level="1"><nlm:affiliation>Department of Science and Technology, Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine, Nanning, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Science and Technology, Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine, Nanning</wicri:regionArea><wicri:noRegion>Nanning</wicri:noRegion></affiliation></author><author><name sortKey="Zai, Junjie" sort="Zai, Junjie" uniqKey="Zai J" first="Junjie" last="Zai">Junjie Zai</name><affiliation wicri:level="1"><nlm:affiliation>Immunology Innovation Team, School of Medicine, Ningbo University, Ningbo, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Immunology Innovation Team, School of Medicine, Ningbo University, Ningbo</wicri:regionArea><wicri:noRegion>Ningbo</wicri:noRegion></affiliation></author><author><name sortKey="Li, Xingguang" sort="Li, Xingguang" uniqKey="Li X" first="Xingguang" last="Li">Xingguang Li</name><affiliation wicri:level="3"><nlm:affiliation>Hubei Engineering Research Center of Viral Vector, Wuhan University of Bioengineering, Wuhan, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Hubei Engineering Research Center of Viral Vector, Wuhan University of Bioengineering, Wuhan</wicri:regionArea><placeName><settlement type="city">Wuhan</settlement><region type="région">Hubei</region></placeName></affiliation></author></analytic><series><title level="j">Journal of medical virology</title><idno type="eISSN">1096-9071</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Betacoronavirus (classification)</term><term>Betacoronavirus (genetics)</term><term>Betacoronavirus (physiology)</term><term>Bungarus (genetics)</term><term>Bungarus (virology)</term><term>Chiroptera (genetics)</term><term>Chiroptera (virology)</term><term>Codon Usage</term><term>Coronavirus Infections (epidemiology)</term><term>Coronavirus Infections (transmission)</term><term>Coronavirus Infections (virology)</term><term>Disease Outbreaks</term><term>Disease Reservoirs</term><term>Evolution, Molecular</term><term>Genome, Viral</term><term>Homologous Recombination</term><term>Host Specificity</term><term>Humans</term><term>Naja naja (genetics)</term><term>Naja naja (virology)</term><term>Phylogeny</term><term>Pneumonia, Viral (epidemiology)</term><term>Pneumonia, Viral (transmission)</term><term>Pneumonia, Viral (virology)</term><term>Snakes (genetics)</term><term>Snakes (virology)</term><term>Spike Glycoprotein, Coronavirus (genetics)</term><term>Zoonoses</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Bungarus (génétique)</term><term>Bungarus (virologie)</term><term>Chiroptera (génétique)</term><term>Chiroptera (virologie)</term><term>Flambées de maladies</term><term>Glycoprotéine de spicule des coronavirus (génétique)</term><term>Génome viral</term><term>Humains</term><term>Infections à coronavirus (transmission)</term><term>Infections à coronavirus (virologie)</term><term>Infections à coronavirus (épidémiologie)</term><term>Phylogénie</term><term>Pneumopathie virale (transmission)</term><term>Pneumopathie virale (virologie)</term><term>Pneumopathie virale (épidémiologie)</term><term>Recombinaison homologue</term><term>Réservoirs d'agents pathogènes</term><term>Serpents (génétique)</term><term>Serpents (virologie)</term><term>Spécificité d'hôte</term><term>Zoonoses</term><term>Évolution moléculaire</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Spike Glycoprotein, Coronavirus</term></keywords><keywords scheme="MESH" qualifier="classification" xml:lang="en"><term>Betacoronavirus</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Betacoronavirus</term><term>Bungarus</term><term>Chiroptera</term><term>Naja naja</term><term>Snakes</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Bungarus</term><term>Chiroptera</term><term>Glycoprotéine de spicule des coronavirus</term><term>Serpents</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Betacoronavirus</term></keywords><keywords scheme="MESH" qualifier="transmission" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Bungarus</term><term>Chiroptera</term><term>Infections à coronavirus</term><term>Pneumopathie virale</term><term>Serpents</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Bungarus</term><term>Chiroptera</term><term>Coronavirus Infections</term><term>Naja naja</term><term>Pneumonia, Viral</term><term>Snakes</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Infections à coronavirus</term><term>Pneumopathie virale</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Codon Usage</term><term>Disease Outbreaks</term><term>Disease Reservoirs</term><term>Evolution, Molecular</term><term>Genome, Viral</term><term>Homologous Recombination</term><term>Host Specificity</term><term>Humans</term><term>Phylogeny</term><term>Zoonoses</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Flambées de maladies</term><term>Génome viral</term><term>Humains</term><term>Phylogénie</term><term>Recombinaison homologue</term><term>Réservoirs d'agents pathogènes</term><term>Spécificité d'hôte</term><term>Zoonoses</term><term>Évolution moléculaire</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The current outbreak of viral pneumonia in the city of Wuhan, China, was caused by a novel coronavirus designated 2019-nCoV by the World Health Organization, as determined by sequencing the viral RNA genome. Many initial patients were exposed to wildlife animals at the Huanan seafood wholesale market, where poultry, snake, bats, and other farm animals were also sold. To investigate possible virus reservoir, we have carried out comprehensive sequence analysis and comparison in conjunction with relative synonymous codon usage (RSCU) bias among different animal species based on the 2019-nCoV sequence. Results obtained from our analyses suggest that the 2019-nCoV may appear to be a recombinant virus between the bat coronavirus and an origin-unknown coronavirus. The recombination may occurred within the viral spike glycoprotein, which recognizes a cell surface receptor. Additionally, our findings suggest that 2019-nCoV has most similar genetic information with bat coronovirus and most similar codon usage bias with snake. Taken together, our results suggest that homologous recombination may occur and contribute to the 2019-nCoV cross-species transmission.</div></front></TEI><affiliations><list><country><li>République populaire de Chine</li></country><region><li>Hubei</li></region><settlement><li>Pékin</li><li>Wuhan</li></settlement></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Ji, Wei" sort="Ji, Wei" uniqKey="Ji W" first="Wei" last="Ji">Wei Ji</name></noRegion><name sortKey="Li, Xingguang" sort="Li, Xingguang" uniqKey="Li X" first="Xingguang" last="Li">Xingguang Li</name><name sortKey="Wang, Wei" sort="Wang, Wei" uniqKey="Wang W" first="Wei" last="Wang">Wei Wang</name><name sortKey="Zai, Junjie" sort="Zai, Junjie" uniqKey="Zai J" first="Junjie" last="Zai">Junjie Zai</name><name sortKey="Zhao, Xiaofang" sort="Zhao, Xiaofang" uniqKey="Zhao X" first="Xiaofang" last="Zhao">Xiaofang Zhao</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/CovidV2/Data/new/Analysis
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000443 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/new/Analysis/biblio.hfd -nk 000443 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= CovidV2
|flux= new
|étape= Analysis
|type= RBID
|clé= pubmed:31967321
|texte= Cross-species transmission of the newly identified coronavirus 2019-nCoV.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/new/Analysis/RBID.i -Sk "pubmed:31967321" \
| HfdSelect -Kh $EXPLOR_AREA/Data/new/Analysis/biblio.hfd \
| NlmPubMed2Wicri -a CovidV2
| This area was generated with Dilib version V0.6.33. |  |